RESUMO
Vaccination against COVID-19 is a highly debated subject that brings confusion due to contradictory information coming from the scientific community and the media. Our aim was to focus on a homogeneous group of students in the healthcare field to assess their intention to vaccinate and the drivers behind this decision. A cross-sectional study was performed in the spring of 2021 in a Medical University in Romania. 725 of the undergraduates that completed an online questionnaire regarding their intention to vaccinate against COVID-19 were included in the study. Univariable analysis and logistic regression were performed on several variables to analyze factors affecting the willingness to vaccinate against COVID-19. In our study sample, 93.1% of students presented a strong intention to vaccinate, out of which the highest proportion belonged to subjects studying general medicine (96%). On logistic regression, we identified the following predictor factors: previous infection with coronavirus, prior vaccination refusal, VAX score, scientifically oriented sources of information and preference for RNA-based technology. Medical students have an increased willingness towards vaccination. Even for them, a highly educated and informed group of subjects, the general attitude towards vaccinations has a strong impact on the choice of COVID-19 vaccination.
Assuntos
Vacinas contra a AIDS , COVID-19 , Vacinas Anti-Haemophilus , Vacinas contra Influenza , Vacinas contra Papillomavirus , Vacinas contra Vírus Sincicial Respiratório , Vacinas contra a SAIDS , Estudantes de Medicina , Vacinas Tíficas-Paratíficas , Vacina BCG , COVID-19/prevenção & controle , Vacinas contra COVID-19/uso terapêutico , Estudos Transversais , Vacina contra Difteria e Tétano , Vacina contra Difteria, Tétano e Coqueluche , Vacinas contra Hepatite A , Vacinas contra Hepatite B , Humanos , Vacina contra Sarampo-Caxumba-Rubéola , RNA , Romênia , Vacinas de Produtos Inativados , Vacinas SintéticasAssuntos
Epidermólise Bolhosa Distrófica , Qualidade de Vida , Índice de Gravidade de Doença , Inquéritos e Questionários , Adolescente , Adulto , Criança , Pré-Escolar , Epidermólise Bolhosa Distrófica/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes , Romênia , Adulto JovemAssuntos
DNA/genética , Dermatite/genética , Desmogleína 1/genética , Hipersensibilidade/genética , Mutação , Síndrome de Emaciação/genética , Pré-Escolar , Análise Mutacional de DNA , Dermatite/complicações , Dermatite/metabolismo , Desmogleína 1/metabolismo , Feminino , Humanos , Hipersensibilidade/complicações , Hipersensibilidade/metabolismo , Índice de Gravidade de Doença , Síndrome de Emaciação/complicações , Síndrome de Emaciação/metabolismoRESUMO
BACKGROUND: The Melkersson-Rosenthal syndrome (MRS) is a very rare clinical entity and its classical form is being characterized by the following triad: facial nerve palsy, swelling of the lips and fissured tongue. However, the monosymptomatic form is more common and the typical manifestation is facial edema and/or enlargement of the lips. CASE REPORT: We report a case of monosymptomatic MRS with a positive biopsy of granulomatous cheilitis. CONCLUSIONS: In the daily practice as a pediatrician, it is not usual to diagnose a patient as having MRS. We consider that this is partly because of misdiagnosis. We therefore believe that this case report will supply additional information, in the scope of recurrent facial paralysis and orofacial edema in both children and adults.
Assuntos
Síndrome de Melkersson-Rosenthal/diagnóstico , Adolescente , Anti-Inflamatórios/uso terapêutico , Edema/etiologia , Edema/patologia , Feminino , Humanos , Síndrome de Melkersson-Rosenthal/complicações , Síndrome de Melkersson-Rosenthal/patologia , Síndrome de Melkersson-Rosenthal/terapia , Língua Fissurada/diagnóstico , Língua Fissurada/patologia , Triancinolona Acetonida/uso terapêuticoRESUMO
BACKGROUND: Multiple cutaneous cylindromas are uncommonly associated with extracutaneous cylindromas. An association between cutaneous cylindromas and salivary gland cylindromas would probably not be fortuitous. CASE REPORT: A 66-year-old man developed multiple cutaneous cylindromas and cylindromas situated in the parotid and submaxillary gland. Histology was similar for both localizations. DISCUSSION: This association was probably not fortuitous as the histology was similar, other cases have been reported in the literature, and recent complaint concerned the development of multiple cutaneous cylindromas and salivary gland cylindromas. Salivary gland cylindromas should be searched for in patients who develop cutaneous cylindromas as they are more aggressive in nature.
